Yes! The work of a professor is very likely to trace to systems engineering experience areas, no matter what topic he or she is teaching! An engineering professor is more likely to qualify than someone teaching in the humanities only because of the process the engineer follows is more likely to include systems thinking. However, if a professor uses systems engineering principles to design and execute a non-technical course, it could still count. It is the process and technical products (e.g., validation plan) that matter, not the specifics of the topic area (aka domain) that matter. 

Here are some of the ways a professor might describe their work experience on a CSEP application:

• Requirements Engineering - Developing a course to meet stakeholder needs
• System Operation and Maintenance - Preparing for and managing results of course delivery 
• Technical Monitoring and Control - Planning for research project assessment and control
• Information and Change Management - Preparing for and executing change management activities for technical writing

Just as a systems engineer's system of interest may be a hardware or software, it may also be a process, a research study, or a course. Like all applicants for CSEP or ESEP, the candidate should review the definitions of the systems engineering experience areas and should describe his or her own experience focusing on what they did, not what the product was.